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The median duration of surgery was 130 min (range, College dating sites 35-300 min). The duration of general anesthesia was 165 min (range, 55-370 min). In the first period (air), the median SpO 2 was 96%(range, 84-100%) and the HR was 84 beats/min (range, 56-160 beats/min). During oxygen supplementation, SpO 2 increased to 99%(range, 94-100%; P < 0.0001), and the HR decreased to 81 beats/min (range, 57-125 beats/min; P < 0.0001). In the second period with air, SpO 2 was 96%(range, 84-100%) and the HR was 85 beats/min (range, 60-144 beats/min;Figure 1A and Figure 1B). There was no significant difference in HR (P = 0.49) or SpO 2 (P = 0.45) between the two periods of air treatment. Overall, 73 of 100 patients responded with decreased HRs with oxygen treatment.
Figure 1. (A) Heart rate and (B) arterial oxygen saturation (SpO 2 ) after oxygen supplementation or air by random order (medians and quartiles)*P < 0.0001 by the Wilcoxon test (n = 100).
Figure 1. (A) Heart rate and (B) arterial oxygen saturation (SpO 2 ) after oxygen supplementation or air by random order (medians and quartiles)*P < 0.0001 by the Wilcoxon test (n = 100).
(Figure 2A and Figure 2B) show the change in HR during oxygen therapy, Delta HR, in relation to prestudy-control SpO 2 and HRparing Delta HR for the defined subgroups of initial HRs, we found a significant reduction in HR with oxygen in the patients with initial HRs of 110 beats/min or more compared with patients with HRs of 70 beats/min or less (P < 0.006) and in patients with HRs between 71 and 109 (P < 0.02). Furthermore, when we applied the Kruskal-Wallis test, we found a significant overall intergroup difference between patients with HRs of 70 beats/min or less, between 71 and 109 beats/min, and 110 beats/min of more (P = 0.02). The linear regression analysis of initial HR versus Delta HR was significant (r = 0.30, P = 0.002), but the Spearman correlation test was not significant (r ( s )= 0.17, P = 0.09).
Profile dos. Changes in heartrate (Delta Hour) immediately following oxygen supplements to possess laid out subgroups regarding arterial outdoors saturation (SpO 2 ) having air (A) and pulse rate (HR) with air (B)(medians and you may quartiles). The Kruskal-Wallis sample produced P = 0.several during the A good and you will P = 0.02 for the B.
Profile dos. Alterations in pulse rate (Delta Time) after fresh air supplementation to have laid out subgroups away from arterial fresh air saturation (SpO 2 ) with air (A) and you will heartbeat (HR) having sky (B)(medians and quartiles). This new Kruskal-Wallis attempt produced P = 0.12 within the An effective and P = 0.02 into the B.
For mathematical analyses, i used the Spearman relationship try, a great linear regression investigation, brand new Wilcoxon finalized score take to, this new Mann-Whitney U take to, and the Kruskal-Wallis attempt fixed getting ties
People that have 1st lowest SpO 2 philosophy got a trend toward an even more noticable lack of Hour which have clean air procedures, even though this wasn’t tall (P = 0.06 and you will P = 0.12;Profile 2A). Outcome of the fresh new linear regression analysis (P = 0.18) and correlation attempt (P = 0.37) anywhere between 1st SpO dos and you can Delta Hr just weren’t extreme.
Thirty-five patients was indeed examined to your postoperative big date step 1, thirty two into the postoperative go out 2, 19 on the postoperative time step 3, and you will 14 towards postoperative big date cuatro. No extreme variations in Time having sky otherwise outdoors (P = 0.step three and you can P = 0.4), changes in Hr (P = 0.5), SpO 2 which have sky or clean air (P = 0.06 and you may P = 0.5), otherwise alterations in SpO 2 (P = 0.052) were discover between customers examined for the various other postoperative days.